Top Hub Genes	Chromosomal Location	Gene Ontology Information
TP53	17p13.1	DNA-binding transcription factor activity and protein heterodimerization activity
ACTB	7p22.1	Identical protein binding and RNA polymerase II cis-regulatory region sequence-specific DNA binding
MMP9	20q13.12	Identical protein binding and metalloendopeptidase
CDKN1A	6p21.2	Ubiquitin protein ligase binding and cyclin binding
BCL2L1	20q11.21	Protein homodimerization activity and protein heterodimerization activity
CASP9	1p36.21	Protein kinase binding and peptidase activity
E2F1	20q11.22	DNA-binding transcription factor activity and transcription factor binding
CASP8	2q33.1	Protein heterodimerization activity and protein-containing complex binding
BCL2L11	2q13	Microtubule binding