Hub Genes
| Top Hub Genes | Chromosomal Location | Gene Ontology Information |
|---|---|---|
| PMS2 | 7p22.1 | ATP hydrolysis activity and endonuclease activity |
| MSH2 | 2p21-p16.3 | Protein homodimerization activity and enzyme binding |
| MSH6 | 2p16.3 | Protein homodimerization activity and ATP hydrolysis activity |
| MLH1 | 3p22.2 | ATP hydrolysis activity and mismatched DNA binding |
| BRCA2 | 13q13.1 | Protease binding and histone acetyltransferase activity |
| PMS1 | 2q32.2 | ATP hydrolysis activity and mismatched DNA binding |
| MSH3 | 5q14.1 | Protein homodimerization activity and single-stranded DNA binding |
| FANCD2 | 3p25.3 | Binding and DNA polymerase binding |
| MEN1 | 11q13 | Sequence-specific DNA binding and transcription cis-regulatory region binding |
| ERCC4 | 16p13.12 | Nucleic acid binding and obsolete protein N-terminus binding |